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Asset 2@3x
  • Overview
  • Services
    • Patient Recruitment
    • Patient Optimization & Enrollment Boost
    • Patient Retention
    • Research Study Rockstar
  • Innovations
    • Performance-Based Pricing
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News / Press

Smart Sourcing: Patient Recruitment & Retention Showcase.

Patient recruitment often breaks down where trust and understanding should begin: communication. Our new AI-driven approach bridges that gap by converting complex, Ph.D.-level protocols into plain-language conversations — tailored to each patient's education level and native language.
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Beyond Awareness: Rethinking Patient Trust And Engagement In The Age Of Decentralized Trials

Over the last several years, the shift to decentralized clinical trials (DCTs) promised a future of flexibility, access, and rapid enrollment...
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The Missing Link In Equal Access: Why Community-Rooted Recruitment Is The Future Of Clinical Trials

For decades, the clinical trial industry has wrestled with the question: How do we make clinical research more accessible?
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4 Proven Strategies To Optimize Patient Enrollment And Avoid Rescue Trials

In the journey to delivering innovative and potentially life-saving therapies to patients, conducting an efficient and high-quality clinical trial with your target patient population is critical...
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Shattering The Status Quo: How CSSi’s AI-Powered Strategy Is Redefining Patient Recruitment Performance

The clinical research industry has long suffered from a problem no one seems able to solve: trials launch late, enroll slowly, and fail to meet recruitment goals—over and over again. For nearly two decades, the metrics have barely moved. Until now.
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Articles

From Transactional To Transformative: Improving The Patient Experience In Clinical Research

As clinical trials grow in volume and diversity, drugs sponsors, CROs, sites, and vendors must adopt strategies that help improve patient engagement, experience, and retention.
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The Future Of Clinical Research Enrollment: A Patient-Centric Approach

Clinical trial enrollment remains one of the biggest challenges in advancing medical research.
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Harnessing Predictive Modeling To Overcome Clinical Trial Enrollment Challenges

Recruiting patients for clinical trials remains one of the most pressing challenges in drug development, with nearly 80% of trials facing delays due to enrollment hurdles.
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White Papers

2025 Trends In Patient Recruitment: From Disruption To Precision

In a post-pandemic clinical research landscape defined by speed, diversity, and decentralized access, patient recruitment remains the single largest cause of trial delays.
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From the front lines to first in patient

From The Front Lines To First-In-Patient: How CSSi’s Local Enrollment Specialists Are Redefining Recruitment Readiness

By: Mike Stratton – President CSSi
April 10, 2025

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Every sponsor wants one thing: the right patients, enrolled quickly, with minimal screen fails. But in today’s complex clinical landscape, recruitment can’t solely rely on passive referrals and generic digital outreach. It demands hands-on expertise, precision screening, and a deep understanding of the patient journey.

That’s where CSSi’s Local Enrollment Specialist (LES) model stands apart—and why leading sponsors and CROs are turning to us to elevate their recruitment strategies.

From Sites to the Field: Why Former CRCs Make the Best LESs

Our LESs are not entry-level recruiters. They’re former Clinical Research Coordinators (CRCs)—people who have sat at the site, reviewed countless I/E criteria, and managed real-world patient logistics. They understand the pressure sites face, the nuances of protocol execution, and the high stakes of every patient interaction.

By pulling talent directly from the front lines of research, we’ve created a field team uniquely equipped to speak the language of both patients and sites—a rare and powerful advantage.

How the LES Model Works

CSSi deploys LESs into specific local markets—often within driving distance of participating sites. Their role is end-to-end:

  • Secondary Screening: Our LESs go beyond surface-level criteria. They perform robust eligibility checks to ensure only the most appropriate patients reach the site, reducing screen failure rates and saving valuable coordinator time.
  • Referral Management: LESs serve as real-time liaisons between the patient, referring sources, and the research site. They actively manage handoffs to prevent drop-off and keep the referral pipeline flowing.
  • Patient Navigation: From answering FAQs to helping coordinate site visits, LESs walk alongside the patient to build confidence and clarity throughout the pre-screening journey.

This isn’t recruitment—it’s clinical-grade patient curation.

Results That Matter

By combining deep protocol knowledge with community-level reach, CSSi’s LES model consistently delivers:

  • Higher-qualified referrals, with a marked reduction in screen fails
  • Accelerated enrollment timelines, especially in competitive indications
  • Improved site satisfaction, due to lower burden and higher show rates
  • Increased retention, as patients are better prepared and supported

Our clients report a measurable impact across both feasibility and operational performance—because when the right patients show up, everything downstream gets easier.

A Model Built for Today’s Challenges

Whether your trial is facing slow enrollment, high screen fails, or sponsor pressure to diversify your patient pool, CSSi’s LES solution is designed to adapt. With a national bench of trained professionals, we can scale up or pivot rapidly across therapeutic areas, geographies, and study phases.

In a market flooded with passive outreach vendors, CSSi brings clinical precision, human connection, and site alignment back into the recruitment equation.

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